Nestor Kippes


Postdoctoral Researcher


  • PhD in Agronomic Sciences, School of Agriculture, University of Buenos Aires, Argentina [2010-2015]
  • BS/MS. Biotechnology, National University of San Martín, Buenos Aires, Argentina [2010]



​I completed my undergraduate studies in the University of San Martin (Argentina) with emphasis in Biotechnology in 2010. The same year I joined the Dubcovsky lab at UC Davis to apply different genetic approaches to understand the regulation of the vernalization requirement in wheat. I received my PhD from the University of Buenos Aires in 2015 under the supervision of Jorge Dubcovsky. ​I am especially interested in the discovery and deployment of genes controlling relevant aspects of development and their utilization to produce improved ​crop varieties. ​

VERNALIZATION 4 gene identification

This project was focused on flowering regulation in wheat, principally understanding the gene networks controlling the vernalization requirement. VRN-D4 is one of the major vernalization genes in wheat and the first aim of this project was to develop a fine map in the VRN-D4 gene region to facilitate the positional cloning and study its interactions with other flowering and photoperiod genes. Ultimately, a better understanding of this regulatory pathway will improve the knowledge of wheat adaptation to different environments. More..

​In the news:
UC Davis Plant Sciences Department
Kansas State University
Yahoo News India
The Tribune India 
Milling Journal
​India Times
Gordon and Betty Moore Fundation


Development and characterization of a spring hexaploid wheat line with non-functional VRN2 alleles
Kippes N, Chen A, Zhang X, Lukaszewski A and Dubcovsky J (2016)
Theoretical and Applied Genetics

Genetic and physical mapping of the earliness per se locus EpsAm1 in Triticum monococcum identifies EARLY FLOWERING 3 (ELF3) as a candidate gene
Alvarez MA, Tranquilli G, Lewis S, Kippes N and Dubcovsky J (2016)
Functional & Integrative Genomics

Identification of the VERNALIZATION 4 gene reveals the origin of spring growth habit in ancient wheats from South Asia
Kippes N, Debernardi JM, Vasquez-Gross HA, Akpinar BA, Budak H, Kato K, Chao S, Akhunov A and Dubcovsky J (2015)​
PNAS [commentary page]

Fine mapping and epistatic interactions of the vernalization gene VRN-D4 in hexaploid wheat
Kippes N, Zhu J, Chen A, Vanzetti L,  Lukaszewski A, Nishida H, Kato K, Dvorak J and Dubcovsky J (2014)
Mol Genet Genomics

Lack of the Matricellular Protein SPARC (Secreted Protein, Acidic and Rich in Cysteine) Attenuates Liver Fibrogenesis in Mice
Atorrasagasti C, Peixoto E, Aquino JB , Kippes N, Malvicini M, Alaniz L, Garcia M, Piccioni F, Fiore EJ, Bayo J, Bataller R, Guruceaga E, Corrales F, Podhajcer O and Mazzolini G (2013)

Antitumor effects of hyaluronic acid inhibitor 4-Methylumbelliferone in an orthotopic hepatocellular carcinoma model in mice
Piccioni F, Malvicini M, Garcia MG, Rodriguez A, Atorrasagasti C, Kippes N, Piedra Buena IT, Rizzo MM, Bayo J, Aquino J, Viola M, Passi A, Alaniz L, Mazzolini G (2012)