Wheat TILLING

Wheat Target Induced Local Lesions In Genome (TILLING) project based on the tetraploid wheat line Triticum turgidum cv. Kronos.  This project entails  targeted re-sequencing of the protein coding regions of over 1500 EMS mutagenized individuals from the Kronos cultivar. In each wheat line, we have identified mutations in protein-coding regions and predicted their effect on protein function. All data is incorporated into a public database.  

The Kronos genomic  sequence is available to all researchers under the Toronto license, information in the release terms and here http://www.nature.com/nature/journal/v461/n7261/full/461168a.html
 
Genome assembly is available from here:
https://opendata.earlham.ac.uk/opendata/data/Triticum_turgidum/EI/v1.1

Ensembl TILLING Tutorial

Account Registration (needed for seed order form access)

Order Form (REQUEST SEEDS)

Documentation

Definitions

Wheat BLAST

Sample TILLING Data for Ensembl (new assembly)  

Sample Search for OLD TILLING Data

TILLING MTA Form

Frequently Asked Questions - FAQs

Financial Support

Capture Design Reference FASTA

UCW Contigs from unmapped reads FASTA

TGAC Contigs for unmapped reads FASTA

GeneAnnotationSummary for Kronos 

GeneAnnotationSummary for Cadenza

Krasileva K V, Vasquez-Gross HA, Howell T, Bailey P, Paraiso F, Clissold L, et al. Uncovering hidden variation in polyploid wheat. Proc. Natl. Acad. Sci. U. S. A. National Academy of Sciences; 2017 Available from: http://www.ncbi.nlm.nih.gov/pubmed/28096351