Wheat rust resistance genes

Rust diseases cause severe yield losses in wheat by reducing photosynthesis, weakening plants, and damaging grain quality. Our lab has been active in the identification and characterization of resistance genes against stripe rust (Puccinia striiformis f. sp. tritici; PST), stem rust (Puccinia graminis f. sp. tritici; Pgt) and leaf rust (Puccinia triticina; Pt). 

Stripe rust resistance 

Mapping:

• Mapping and validation of QTL which confer partial resistance to broadly virulent post-2000 North American races of stripe rust in hexaploid wheat  (Lowe et al. 2011 TAG)
• A Genome-Wide Association Study of Resistance to Stripe Rust (Puccinia striiformis f. sp. tritici) in a Worldwide Collection of Hexaploid Spring Wheat (Triticum aestivum L.) (Maccaferri et al 2015 G3)
• Mapping QTL for resistance to new virulent races of wheat stripe rust from two Argentinean wheat cultivars (Cobo et al. 2018 Crop Science)

Yr36

• Wheat Stripe Rust Resistance Protein WKS1 Reduces the Ability of the Thylakoid-Associated Ascorbate Peroxidase to Detoxify Reactive Oxygen Species (Gou et al. 2015 TPC)
• A kinase-START gene confers temperature-dependent resistance to wheat stripe rust (Fu et al. 2009 Science)

Yr78: 

• High-resolution mapping of Yr78, an adult plant resistance gene to wheat stripe rust (Dang et al 2022, Plant Genome)
• Validation and characterization of a QTL for adult plant resistance to stripe rust on wheat chromosome arm 6BS (Yr78) (Dong et l. 2017 TAG)
• Durum wheat with Yr78 and common wheat with Yr78 and Yr36 in coupling show enhanced stripe rust resistance (Dang et al. 2025 Crop Science)

Yr48:

• Stripe rust resistance gene Yr34 (synonym Yr48) is located within a distal translocation of Triticum monococcum chromosome 5A^mL into common wheat (Chen et al, 2021 TAG)

Stem rust resistance

Sr35:

• Dissection of Cell Death Induction by Wheat Stem Rust Resistance Protein Sr35 and Its Matching Effector AvrSr35 (Bolus et al. 2020 MPMI)
• Variation in the AvrSr35 gene determines Sr35 resistance against wheat stem rust race Ug99 (Salcedo et al. 2017 Science)
• Identification of Wheat Gene Sr35 That Confers Resistance to Ug99 Stem Rust Race Group (Saintenac et al. 2013 Science)
• Genetic Maps of Stem Rust Resistance Gene Sr35 in Diploid and Hexaploid Wheat (Zhang et al. 2010 Crop Science)

Sr13:

• Identification and characterization of Sr13, a tetraploid wheat gene that confers resistance to the Ug99 stem rust race group (Zhang et al. 2017 PNAS)
• Genetic mapping of stem rust resistance gene Sr13 in tetraploid wheat (Triticum turgidum ssp. durum L.) (Simons et al. 2010 TAG)

Sr60:

• Wheat gene Sr60 encodes a protein with two putative kinase domains that confers resistance to stem rust (Chen et al. 2019 New Phyt)
• Mapping and characterization of wheat stem rust resistance genes SrTm5 and Sr60from Triticum monococcum (Chen et al. 2017 TAG)

Leaf rust resistance

Lr47:

• Cloning of the wheat leaf rust resistance gene Lr47 introgressed from Aegilops speltoides (Li et al. 2023 Nature Comm)
• Agronomic and Quality Evaluation of Common Wheat Near‐Isogenic Lines Carrying the Leaf Rust Resistance Gene Lr47 (Brevis et al. 2008 Crop Science)